SIREUS ENTREPRENEURS forum Success Stories: Pioneering Solutions in Medicine, AI, and Biotech

Published January 3rd, 2024. Text by Edith Malmberg, SIREUS

SIREUS ENTREPRENEURS forum Success Stories: Pioneering Solutions in Medicine, AI, and Biotech



Last year in February, the SIREUS Entrepreneurs forum was held in Denver in connection with Destination Startup. The event gave companies connected to Swedish SIREUS member universities the opportunity to connect with businesses, investors, research institutions, federal laboratories and key opinion leaders in the research and innovation ecosystem in both Colorado and Arizona. The week-long immersion was hosted by SACC-Colorado, SACC-Arizona and The University of Colorado Boulder in conjunction with the 2023 Destination Startup conference.

As we’re nearing this year’s event we’ve interviewed several of the participating companies about their experiences in Colorado:
  • sireus-event-logga-2
  • sireus-event-logga-5


Photo of the delegation of Swedish Start-ups in Denver


Participating companies were from SIREUS members Lund University, Stockholm University and Uppsala University.

"It was quite a valuable experience for us to network with different companies, investors and opinion leaders. We became exposed to a set of American investors who really helped us move the needle forward in terms of how we present our company, as well as giving us exposure to their American investor networks."

​​​​​​​
- Leo Holmgren, CEO

“We had the chance to give a short pitch to a crowd of about 400 people together with the rest of the Swedish delegation. We got some great contacts from the events and the experience really helped us set our mindset and prepare us for future fundraising activities."


​​​​​​​
Lucas Ferreira, CEO

“I think that one of the highlights was listening to a panel of Nordic companies telling their stories about transitioning their businesses to the United States. This gave us more energy and inspiration to make the same transition in the future. Since we plan to launch our product in the United States the entire journey to Colorado with SIREUS was very valuable to us.”
​​​​​​​
Nelida Leiva Eriksson, CEO

Interview with Leo Holmgren, CEO of TIRmed Pharma

TIRmed PharmaTIRmed Pharma
Pharmacy
Pharma, TIRmed Pharma
TIRmed Pharma was established by Professor Anna-Lena Spetz from Stockholm University. During her research, she identified an oligonucleotide with immunomodulatory effects, which later has been shown to display disease modifying effects against inflammatory skin diseases. The technology developed by TIRmed Pharma is the result of years of dedicated research. Their active compound effectively inhibit the uptake of pro-inflammatory agents into specific endosomal compartments, thereby impeding the activation of innate immune responses. This targeted intervention leads to a beneficial reduction of pro-inflammatory cytokines, subsequently reducing inflammation. Furthermore, the oligonucleotide indirectly inhibit overactive T-cells, leading to long-lasting effects.

The company is currently developing a new generation of treatments against inflammatory skin disorders, primarily targeting Atopic Dermatitis. After only 5 topical applications in total, they have data which suggest long-lasting symptom relief for over 8 months.

“What I believe makes our product unique is that usually when you think about topical treatments, for any type of skin disorder, they’re usually associated with once or twice daily application. We have proof of concept data that shows that the patient might only need around 10 applications, i.e. 1-2 treatments per year, with this product.” - Leo Holmgren, CEO of TIRmed Pharma
How has participating in SIREUS Entrepreneurs Forum and Destination Startup® impacted your company's visibility and networking opportunities?
“I think it was a great learning experience for us. Americans are usually highly talented when it comes to pitching and advocating for their companies. As a life science company, we are sometimes a bit more hesitant to “stick out our noses” but we are really trying to embed that optimism, ambition and vision that many of the American entrepreneurs have. It was also quite a valuable experience for us to network with different companies, investors and opinion leaders. We became exposed to a set of American investors who really helped us move the needle forward in terms of how we present our company, as well as giving us exposure to their American investor networks. We have been able to engage further with these investors and, from a long-term perspective, the connections we gained in the U.S. will be valuable to us as we continue to expand."

"For us, it's important to start becoming exposed towards the FDA, as early as possible, so that we align our strategy with their requirements. Through this network that we have been able to develop in the U.S., we have access to potential agents who could potentially advocate for TIRmed Pharma. This is key when you want to engage with the FDA.”

What was the highlight of your trip- which memory stands out the most?
“I think that the startup conference in Denver, that we were invited to, was one of the highlights of the trip. We got to listen to many companies in their early stages (seed stages and pre-seed stages) pitching their ideas, and they did it in a drastically different way than Swedish companies would do. By listening to them we gained a better understanding of how the American investors think and it was fun to get the chance to pitch for the American investors. Pitching your company in 30 seconds is a challenge on its own, but the key challenge was how to make statements that were sufficiently attractive to make the investors want to engage further with the company.”

Based on your experience, what advice would you give to other startups attending next year’s Entrepreneurs forum?
“I think that you really need to capitalize on engaging with as many of the American counterparts as you possibly can. Essentially, make sure to really jump on every opportunity. The business environment is open and friendly and we found that people are willing to collaborate. It is beneficial to follow up with these connections after the event, because even if some investors don’t necessarily have you as a target, they often have other people within their network who could potentially be interested in your company.”

Can you articulate the long-term vision for your company and the impact you hope to achieve in your industry or community?
“Ultimately, we would like to become the second line treatment after corticosteroids essentially becoming one of the primary products available for the vast majority of people who suffer from Atopic Dermatitis. I think that there is an outspoken need for new treatments for the 90% of people who don’t want or aren’t eligible for the systemic treatments. Becoming one of the new leading players within Atopic Dermatitisis our main goal.”

Interview with Lucas Ferreira, CEO of Inceptron

Inceptron AIInceptron AI
AI machine
Inceptron AI
The use of AI-driven video and image analysis is expanding at a swift pace, but so has the cloud costs, inference runtimes, and energy consumption. Inceptron has patented a technology that enables the customization of on-demand hardware, exclusively dedicated to AI networks. For early adopters, this translates into a remarkable 50% reduction in cloud costs, an acceleration in inference runtimes, and an impressive 60% or more decrease in the energy consumption of algorithms. Inceptron is co-founded by Steffen Malkowsky and Lucas Ferreira who strive to develop a solution for AI computing using reconfigurable hardware (FPGAs) in the cloud. The idea behind Inceptron was initially a spin-off from Lucas Ferreira’s PhD research at Lund University within machine learning.

“The cost of processing the machine learning algorithms on the cloud are going through the roof these days. Some of the startups that we’ve talked to are spending hundreds of thousands of euros just on the processing and around 30% of all solar power in the world is currently being eaten by the processing of these algorithms in the cloud overall. Inceptron can help our customers compute the same thing at a fraction of the cost and save at least 60% of the power consumption.” 
How has participating in SIREUS Entrepreneurs Forum and Destination Startup® impacted your company's visibility and networking opportunities?
“For us it was a very interesting experience that gave us the chance to connect with other entrepreneurs in the U.S. as well as discover their mindsets and listen to their pitches. We had the chance to give a short pitch to a crowd of about 400 people together with the rest of the Swedish delegation. We got some great contacts from the events and the experience really helped us set our mindset and prepare us for future fundraising activities. On the commercial side, we connected with other companies there that could be potential customers for us in the future as we continue to expand.”

What was the highlight of your trip- which memory stands out the most?
“Throughout the trip we got to learn a lot about both Denver and Boulder. As we were very early on in our journey as a company, the highlight of the trip was the pitch practice as well as getting the chance to speak with American investors and potential customers. It was very valuable for us to get a sense of what was “to come”. In Boulder we also had the opportunity to meet a few Swedish companies that have transitioned to the U.S. market and it was very inspiring to listen to the founders' stories.”

Based on your experience, what advice would you give to other startups attending next year’s Entrepreneurs forum?
“Pitch, pitch, pitch! Do it all the time. The most interesting conversations that I had were during the mingles. Just get out there and try to talk to everybody, that is how you can make the most out of your trip. It is also very valuable to listen to how other startups pitch their ideas to the investors in order to really learn more about both the American market and mindset.”

Can you articulate the long-term vision for your company and the impact you hope to achieve in your industry or community?
“We want to provide the technology that helps AI become available for everybody, at lower costs and with greater power efficiency.”

Interview with Nelida Leiva Eriksson, CEO of Ironic Biotech

Ironic Biotech companyIronic Biotech company
Iron substitute pills
Ironic Biotech iron supplement
The idea behind Ironic Biotech originated from Dr. Nelida Leiva Eriksson's own struggle with iron deficiency—an issue prevalent among numerous people in the world. Faced with the challenge, she tried various iron substitute pills available on the market at the time, only to realize their inadequacy and the associated digestive problems they triggered in many individuals.
​​​​​​​
Driven by the determination to find a more effective and tolerable solution, Dr. Leiva Eriksson, a seasoned researcher specializing in blood substitutes, embarked on a journey to develop a groundbreaking remedy for iron deficiency-induced fatigue. The irony of her situation, being an expert in the field of blood substitutes yet grappling with a common health concern, led to the fitting and memorable name, Ironic Biotech.

The prevalence of IDA demands urgent attention and innovative interventions, as the previous options fall short of meeting the diverse needs of those grappling with this condition. Ironic Biotech's mission to come up with a groundbreaking remedy is therefore quite important, considering the widespread and pressing health concerns linked to IDA.
How has participating in SIREUS Entrepreneurs Forum and Destination Startup® impacted your company's visibility and networking opportunities?
“I think that participating in the SIREUS Entrepreneurs forum gave me and my partner a deeper understanding of the relation between time and money. In Sweden we had previously talked to a lot of angel investors, where things usually move at a slower pace, which is something that I am very accustomed to as a researcher in academia. It was very interesting to go to Denver and listen to the pitches and speak with other types of investors, we learned that time is as valuable as the money aspect. We realized that there were many investors who value time more than funding. As a mother with teenage daughters, I would like to see my product on the market soon, and the time aspect is something I really value."

"We also got contacts from the entrepreneurs forum that are very valuable for us. We have been talking to a couple of investors in the U.S. as we’re currently doing our pre/seed run round with our Nordic investors. We still have good contact with the U.S. investors and hopefully next year during this time we will be ready to launch our product.”

What was the highlight of your trip- which memory stands out the most?
“I think that one of the highlights was listening to a panel of Nordic companies telling their stories about transitioning their businesses to the United States. Listening to their stories really helped us visualize our own journey to the U.S. market in the future and reflect more about which path we want to go down. This gave us more energy and inspiration to make the same transition in the future. Since we plan to launch our product in the United States the entire journey to Colorado with SIREUS was very valuable to us.”

Based on your experience, what advice would you give to other startups attending next year’s Entrepreneurs forum?
“I think the first thing is to be open minded, do not go with preformed ideas. People usually have an idea about how to run their business and what their company stands for, but even though you have these pre-set ideas about your company, make sure to make the most of your trip. Go and listen to everyone and speak to people that are in different sectors than you. I think it is really important to be able to balance having a clear idea of what you’re willing to sell and remaining open to new impressions and ideas.”

Can you articulate the long-term vision for your company and the impact you hope to achieve in your industry or community?
“My company is at the intersection between food and health. Our product can be used both as a food ingredient but also in the pharmacy. If we talk broadly, the product is within nutrition, but we want this nutrition to come from the food people eat. For us an important aspect is to really give people good health through good food. In special cases however, such as with pregnant women or people with chronic kidney diseases, we want to be able to provide them with the pharma version of our product. Long term I want to see our company as leaders within bioengineered nutrition. Today the ratio of nutrients is lower than it was historically, at the beginning of the century a loaf of bread had more nutrition than it has today. We want to use the technology that exists today to make sure that nutrition is accessible to all layers of society– small children, pregnant women, and the elderly.”













Want to learn more about TIRmed Pharma?


University: Stockholm University

​​​​​​​Contact: Leo Holmgren, [email protected]
















































​​​​​​​

Want to learn more about Inceptron?


University: Lund University

​​​​​​​Contact: Lucas Ferreira, [email protected]


































Want to learn more about Ironic?


University: Lund University

Contact: Nélida Leiva Eriksson, [email protected]

​​​​​​​Hans Holm, [email protected]



SIREUS Entrepreneurs forum 2024


Join the SIREUS Entrepreneurs Forum for a unique chance to connect with local organizations, partners, investors, and mentors in Boulder and Denver. Gain exposure and validation for your ideas, refine your business strategy, and build valuable connections in this powerhouse of research and innovation. With private meetings tailored to your needs, return to Sweden with insights and a network ready for your U.S. market entry. The event takes place from March 18-22, 2024, in the thriving entrepreneurial ecosystem of Boulder, Colorado.

​​​​​​​

More about the SIREUS Project


​​​​​​​SIREUS, a collaboration between The Swedish American Chambers of Commerce (SACC-USA) and 13 Swedish universities, focuses on knowledge exchange in innovation, science, and entrepreneurship, as well as talent mobility for students and researchers between Sweden and the U.S. 
​​​​​​​
The Embassy of Sweden in Washington, D.C., and the Swedish Institute support the project through advice and contacts.   


​​​​​​​

About Entrepreneurs forum


The SIREUS ENTREPRENEURS forum offers a unique opportunity to engage with a diverse ecosystem of innovators, accelerate your growth, and explore the possibilities for international expansion. It is an exclusive opportunity for deep tech startups spun out of universities in the SIREUS network to accelerate their international development. Participants will get introduced to early-stage deep tech investors in the U.S., potential customers or U.S. partners as well as other key resources for entering the U.S. market such as legal experts, startup accelerators and relevant industry organizations. 
​​​​​​​